The CryoMill is tailored for cryogenic grinding. The grinding jar is continually cooled with liquid nitrogen from the integrated cooling system before and during the grinding process.
Thus the sample is embrittled and volatile components are preserved. The liquid nitrogen circulates through the system and is continually replenished from an Autofill system in the exact amount which is required to keep the temperature at -196 °C.
Powerful impact ball milling results in a perfect grinding efficiency. The Autofill system avoids direct contact with LN2 and makes cryogenic grinding very safe. Its versatility (cryogenic, wet and dry grinding at room temperature) makes the CryoMill the ideal grinder for quantities up to 20 ml.

You may also be interested in the High Energy Ball Mill Emax, an entirely new type of mill for high energy input. The unique combination of high friction and impact results in extremely fine particles within the shortest amount of time.

Application Examples

animal feed, bones, chemical products, food, hair, oil seeds, paper, plant materials, plastics, sewage sludge, soils, tablets, textiles, tissue, waste samples, wood, wool, ... continue to application database

Product Advantages

  • powerful cryogenic grinding by impact and friction, up to 30 Hz
  • 3 different grinding modes (cryogenic, dry or wet at ambient temperature)
  • closed LN2-system (autofill) for enhanced safety, avoids any contact of the user with LN2
  • screw-top grinding jars for convenient, leak-proof operation
  • wide range of accessories including various LN2 feeding systems, jar and ball sizes, adapter racks, materials
  • low LN2-consumption
  • clearly structured user interface, memory for 9 SOPs
  • programmable cooling and grinding cycles (10 s to 99 min)
  • ceramic jar available


Applications size reduction, mixing, homogenization, cell disruption
Field of application agriculture, biology, chemistry / plastics, construction materials, engineering / electronics, environment / recycling, food, geology / metallurgy, glass / ceramics, medicine / pharmaceuticals
Feed material hard, medium-hard, soft, brittle, elastic, fibrous
Size reduction principle impact, friction
Material feed size* ≤ 8 mm
Final fineness* ~ 5 µm
Batch size / feed quantity* max. 20 ml
No. of grinding stations 1
Setting of vibrational frequency digital, 5 - 30 Hz (300 - 1800 min-1)
Typical mean grinding time 10 min / 4 min (cooling / grinding)
Dry grinding yes
Wet grinding yes
Cryogenic grinding yes
Cell disruption with reaction vials yes
Self-centering clamping device yes
Type of grinding jars screw top design
Material of grinding tools hardened steel, stainless steel, zirconium oxide, PTFE
Grinding jar sizes 5 ml / 10ml / 25 ml / 35 ml / 50 ml
Autofill 50 l
Setting of grinding time digital, 30 s - 99 min
Storable SOPs 9
Electrical supply data 100-240 V, 50/60 Hz
Power connection 1-phase
Protection code IP 30
Power consumption 260 W
W x H x D closed 395 x 373 x 577 mm (D: 710 mm with exhaust tube)
Net weight ~ 45 kg
Standards CE

Please note:
*depending on feed material and instrument configuration/settings

Function Principle

The grinding jar of the CryoMill performs radial oscillations in a horizontal position. The inertia of the grinding balls causes them to impact with high energy on the sample material at the rounded ends of the grinding jar and pulverize it.
The grinding jar is continually cooled with liquid nitrogen from the integrated cooling system before and during the grinding process.

Subject to technical modifications and errors